Journal: PLoS ONE
Article Title: Immunosuppressive Activity of Daphnetin, One of Coumarin Derivatives, Is Mediated through Suppression of NF-κB and NFAT Signaling Pathways in Mouse T Cells
doi: 10.1371/journal.pone.0096502
Figure Lengend Snippet: Histological changes in right ear of mice at 24 h following elicitation with DNFB. (A) Control group: microphotograph showed normal structure of the ear; (B) DTH group: microphotograph showed histopathologic changes (edema, infiltration of inflammatory cells) of the ear; (C) CTX group; Daphnetin group (D: 5 mg/kg; E; 10 mg/kg; F: 20 mg/kg): microphotograph showing decreased histopathologic changes of the ear.
Article Snippet: Goat anti-mouse IgG, Goat anti-mouse FITC, Peroxidase-conjugated AffiniPure goat anti-mouse IgG (H + L) were purchased from Protein Tech Group, 2, 4-Dinitrofluorobenzene (DNFB) and cyclophosphamide (CTX) were obtained from Sigma-Aldrich (St. Louis, MO).
Techniques: